Ep.17 – Dominic D’Agostino, PhD: Boosting Brain Function & Fat Loss With A Ketogenic Diet Part 1 of 2 - You, Optimized. Radio
Want exclusive video interviews? Please become a Patron! With your help, I can expand this podcast and deliver better content!Dominic is an Assistant Professor in the Department of Molecular Pharmacology and Physiology at the University of South Florida (USF) Morsani College of Medicine and also a Senior Research Scientist at the Institute for Human and Machine Cognition (IHMC). In his lab at the University of South Florida, Dr. Dominic D'Agostino and his team develop and test therapies that target specific pathways linked to seizure disorders, neurodegenerative diseases, metabolic dysregulation, cancer, muscle wasting and exercise performance.Not only is Dominic D'Agostino a researcher, professor, and neuroscientist, he's also a biohacker and athlete. In this episode we discuss using calorie restriction, fasting, and the ketogenic diet to boost brain function, fat loss, athletic performance, and for therapeutic purposes, particularly regarding brain-related diseases and cancer.The primary focus of his laboratory is developing and testing metabolic therapies, including ketogenic diets, ketone esters and natural and synthetic molecules to target metabolic processes. His research also explores the use of these therapies for a broad range of disorders. D’Agostino’s laboratory uses in vivo and in vitro techniques to understand the physiological, cellular and molecular mechanism of metabolic therapies. His research is supported by the Office of Naval Research (ONR), Department of Defense (DoD), private organizations and foundations.So if you or somebody you know is suffering through neurodegenerative disease, diabetes, cancer or you just want to avoid these things in the future, this episode is definitely one you’ll want to pay attention to and share with those who might really need this info. What You'll Hear In This Episode02:35 Defining nutritional ketosis and beta oxidation & how it can help you burn fat. 05:40 Is it beneficial to be in ketosis all the time? 07:10 Why ketosis may or may not be hard on your liver and what you can do about it. 09:25 How your body processes medium chain triglycerides (MCT) and how much to take. 11:17 The factors that determine how your liver processes fat. 12:55 Who should really consider utilizing a ketogenic diet for health reasons. 14:40 The ketogenic diet & brain energy metabolism.