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20 minutes | Oct 20, 2020
#10- Gene editing CRISPR-Cas9, Coronavirus spilling from bats to humans, COVID-related brain effects
On Episode #10, here are the main topics:1. The 2020 Nobel prize in Chemistry was awarded for the discovery of a genetic engineering technique. With all its benefits, the technique has some seriously concerned about its ethical implications.2. Studies suggest that coronavirus could lead to neurological illnesses3. New research reveals why coronavirus that once lived harmlessly in bats and other wildlife – has become uncontrollable once it jumped the species barrier and entered humans.ReferencesDoudna, J. A., & Charpentier, E. (2014). The new frontier of genome engineering with CRISPR-Cas9. Science, 346(6213).Frontera, J. A., Sabadia, S., Lalchan, R., Fang, T., Flusty, B., Millar-Vernetti, P., ... & Morgan, N. (2020). A Prospective Study of Neurologic Disorders in Hospitalized COVID-19 Patients in New York City. Neurology.Alejandro Berrio, Valerie Gartner, Gregory A. Wray. Positive selection within the genomes of SARS-CoV-2 and other Coronaviruses independent of impact on protein function. PeerJ, 2020; 8: e10234
14 minutes | Oct 7, 2020
#9 - $23m toilet headed for space, Nobel Prize 2020, Stockholm wastewater & COVID-19
On Episode#9, we discuss:1. NASA launches a 23m titanium toilet headed to the International Space Station2. The 2020 Nobel prize for Medicine awarded for the discovery of Hepatitis C virus3. What does the wastewater in Stockholm, Sweden tell about the uptick in coronavirus cases? References:1. https://apnews.com/article/business-spacex-archive-moon-f06581fe70515ae7608304af8e6a44fb2. Law, John Lok Man, et al. "A hepatitis C virus (HCV) vaccine comprising envelope glycoproteins gpE1/gpE2 derived from a single isolate elicits broad cross-genotype neutralizing antibodies in humans." PloS one 8.3 (2013): e59776. 3. Lundkvist, Åke, Stefan Hanson, and Björn Olsen. "Pronounced difference in Covid-19 antibody prevalence indicates cluster transmission in Stockholm, Sweden." Infection ecology & epidemiology 10.1 (2020): 1806505.
18 minutes | Sep 29, 2020
#8 - COVID vaccine & Megafires
On Episode#8, we talk about COVID vaccine updates, and Mega-Fires across the US1. One candidate vaccine fore COVID-19 showed possible neurological sideeffects. What does this mean for the other vaccines in the pipeline currently in Phase 3?2 New research explores the reason for the mega-wildfires that has moved across western United Sates.. and what it says about future extreme events moving further throughout the country over time.ReferencesKeech, C., Phase 1–2 Trial of a SARS-CoV-2 Recombinant Spike Protein Nanoparticle Vaccine, NEJM, 2020 Alizadeh, M., et al, A century of observations reveals increasing likelihood of continental-scale compound dry-hot extremes, Science Advances 2020Jia, Shenyue, et al. "Patterns of population displacement during mega-fires in California detected using Facebook Disaster Maps." Environmental Research Letters (2020).Burke, Marshall, et al. The Changing Risk and Burden of Wildfire in the US. No. w27423. National Bureau of Economic Research, 2020.
16 minutes | Sep 19, 2020
#7 - Risky business with Tylenol, Cardio and BrainPower, Longterm effects of Pandemics
ON Episode#7, here are the main headlines:1. Got a bad ache? Did you take a Tylenol? New research finds While acetaminophen, the main ingredient in Tylenol is helping you deal with your headache, it may also be influencing your judgement, making you more willing to take risks.2. In fitness research, a systematic review of dozens of different studies show that performing any form of aerobic exercise before engaging in a learning activity improves the learning ability and storage in memory.3. What are the longterm effects of pandemics? A report finds that effects of pandemics in history have lasted for 4 decadesReferences:1. Alexis Keaveney, Ellen Peters, Baldwin Way. Effects of acetaminophen on risk taking. Social Cognitive and Affective Neuroscience, 20202. Peter Blomstrand and Jan Engvall. "Effects of a Single Exercise Workout on Memory and Learning Functions in Young Adults—A Systematic ReviewE." Translational Sports Medicine (First published: August 08, 2020) 3. Jordà, Òscar, Sanjay R. Singh, and Alan M. Taylor. Longer-run economic consequences of pandemics. No. w26934. National Bureau of Economic Research, 2020.
18 minutes | Sep 15, 2020
#6 - Marshmallow Test v 2.0, COVID transmission during normal speech
On episode #6, here are the main ideas:1. Is a mask really necessary when just talking? Can the coronavirus be transmitted through normal speech? A new study uses lasers to look at how respiratory droplets are emitted during normal speech.2. Scientists revisit the famous psychology experiment the marshmallow test, revealing new insights into self-control behavior and how it may have something to do with managing our reputation, and its relevance for the future.References Stadnytskyi, Valentyn, et al. "The airborne lifetime of small speech droplets and their potential importance in SARS-CoV-2 transmission." Proceedings of the National Academy of Sciences 117.22 (2020): 11875-11877.Bax, Adriaan, et al. "SARS-CoV-2 transmission via speech-generated respiratory droplets." The Lancet Infectious Diseases (2020).Wells, William F. "On air-borne infection: Study II Droplets and Droplet nuclei." American journal of Epidemiology 20.3 (1934): 611-618.Anfinrud, Philip, et al. "Visualizing speech-generated oral fluid droplets with laser light scattering." New England Journal of Medicine (2020).Ma, Fengling, et al. "Delay of Gratification as Reputation Management." Psychological Science (2020): 0956797620939940.Mischel, Walter, Ebbe B. Ebbesen, and Antonette Raskoff Zeiss. "Cognitive and attentional mechanisms in delay of gratification." Journal of personality and social psychology 21.2 (1972): 204.
17 minutes | Sep 12, 2020
#5- Calorie Restriction, Sleep Loss, and Competition vs Cooperation
On this episode #5, we discuss recent research news that affects our lives and future. On this episode, here are the main headlines: 1. Feeling angry lately? New research suggests that a good night of sleep may be just what you need.2. Have you been intermittent fasting? cutting calories have been linked to many health benefits including longer lifespan. But why? A new study shows how calorie intake may affect your core body temperature.3. Finally, if you are working on self-improvement goals, is competition against others always the better strategy over cooperation with others? New study using fitness trackers sheds some light on this age-old question… compete or cooperate? Journal References1. Krizan, Z., Miller, A., & Hisler, G. (2020, April). Does losing sleep unleash anger? Sleep (Vol. 43, pp. A105-A105)2. Carlos Guijas, J. Rafael Montenegro-Burke, Rigo Cintron-Colon, Xavier Domingo-Almenara, Manuel Sanchez-Alavez, Carlos A. Aguirre, Kokila Shankar, Erica L.-W. Majumder, Elizabeth Billings, Bruno Conti, Gary Siuzdak. Metabolic adaptation to calorie restriction. Science Signaling, 2020; 13 (648): eabb2490 DOI: 10.1126/scisignal.abb24903. Wolf, T., Jahn, S., Hammerschmidt, M., & Weiger, W. H. (2020). Competition versus cooperation: How technology-facilitated social interdependence initiates the self-improvement chain. International Journal of Research in Marketing.
17 minutes | Sep 8, 2020
#4- Robot nurses, Edible devices, Quantum internet, Battery charging with bodyheat
On the episode, we discuss these topics:1. Robots are being trained to perform contact-free measurements of patients’ vital signs.2. Can your cell-phone be re-charged using your body heat?3. How does a baseball player know when to swing and when not to? We discuss the neuroscience behind split-second decision-making.4. A biotech company develops an ingestible device that fixes itself in the stomach.5. Finally, what is quantum internet and can it make internet hacking a thing of the past? ReferencesRobot takes contact-free measurements of patients’ vital signshttps://news.mit.edu/2020/spot-robot-vital-signs-0831Burmistrov, I., Gorshkov, N., Kovyneva, N., Kolesnikov, E., Khaidarov, B., Gopalu, K., ... & Gorokhovsky, A. (2020). High seebeck coefficient thermo-electrochemical cell using nickel hollow microspheres electrodes. Renewable Energy. Ming Ma, Gregory L. Futia, Fabio M. Simoes de Souza, Baris N. Ozbay, Isabel Llano, Emily A. Gibson, Diego Restrepo. Molecular layer interneurons in the cerebellum encode for valence in associative learning. Nature Communications, 2020; 11 (1) DOI: 10.1038/s41467-020-18034-2Abramson, A., Dellal, D., Kong, Y. L., Zhou, J., Gao, Y., Collins, J., ... & Frederiksen, M. R. (2020). Ingestible transiently anchoring electronics for microstimulation and conductive signaling. Science Advances, 6(35), eaaz0127.Joshi, S. K., Aktas, D., Wengerowsky, S., Loncaric, F., Neumann, S. P., Liu, B., ... & Stipcevic, M. (2020, May). A trusted-node-free eight-user metropolitan quantum communication network. Science Advances (2020) DOI: 10.1126/sciadv.aba0959
17 minutes | Sep 4, 2020
#3- Pentagon & Google AI, COVID vaccine arrival, Traffic in space, Handgrip strength diagnosis
On today's episode, we discuss:1. The Pentagon and Google Artificial Intelligence are teaming up to test on military veterans.2. Hundreds of astronomers are worried that traffic in space will change our view of the nightsky forever.3. Can your hand grip strength tell if you are at the risk of a disease?4. Psychologists reveal which teenagers are more likely to be cyberbullies.5. CDC announces that states should be ready to distribute vaccines by Nov 1. We discuss the state of COVID vaccines in the drug pipeline currently in Phase 3.References1. https://www.ibtimes.co.uk/cancer-research-benefit-cutting-edge-ai-pentagon-seeks-help-google-16828362. Walker, C. et al, Impact of satellite constellations on optical astronomy and recommendations towards mitigation, August 2020https://aas.org/sites/default/files/2020-08/SATCON1-Report.pdf3. Setor K. Kunutsor, Ari Voutilainen, Jari A. Laukkanen. Handgrip strength improves prediction of type 2 diabetes: A prospective cohort study. Annals of Medicine, 20204. Laura Grunin, Gary Yu, Sally S. Cohen. The Relationship Between Youth Cyberbullying Behaviors and Their Perceptions of Parental Emotional Support. International Journal of Bullying Prevention, 20205. https://www.nytimes.com/interactive/2020/science/coronavirus-vaccine-tracker.html6. van Doremalen, N., Lambe, T., Spencer, A. et al. ChAdOx1 nCoV-19 vaccine prevents SARS-CoV-2 pneumonia in rhesus macaques. Nature (2020).
16 minutes | Sep 3, 2020
#2- New galaxies, Weight loss, Body clock, Voting-By-Mail and Blockchain
We will discuss these recent discoveries on Episode # 2 1. A new galaxy that looks like the Milky Way has been discovered that challenges existing theories of the evolution of galaxies.2. Its not enough to lose weight to stay fit, but when you lose weight matters.3. Your body keeps track of time without checking a clock.4. Is voting-by mail safe? Does cryptocurrencies offer any insight for online voting in the future? ReferencesRizzo, F., Vegetti, S., Powell, D. et al. A dynamically cold disk galaxy in the early Universe. Nature 584, 201–204 (2020). Yongli Shan, John H. Abel, Yan Li, Mariko Izumo, Kimberly H. Cox, Byeongha Jeong, Seung-Hee Yoo, David P. Olson, Francis J. Doyle, Joseph S. Takahashi. Dual-Color Single-Cell Imaging of the Suprachiasmatic Nucleus Reveals a Circadian Role in Network Synchrony. Neuron, 2020Xie W, Lundberg DJ, Collins JM, et al. Association of Weight Loss Between Early Adulthood and Midlife With All-Cause Mortality Risk in the US. JAMA Netw Open. 2020;3(8):e2013448.Thompson, D. M., Wu, J. A., Yoder, J., & Hall, A. B. (2020). Universal vote-by-mail has no impact on partisan turnout or vote share. Proceedings of the National Academy of Sciences.Park, S., Specter, M., Narula, N., & Rivest, R. L. (2020). Going from bad to worse: from internet voting to blockchain voting.
23 minutes | Sep 1, 2020
#1- Dreams, Marie Kondo, Brain-Computer Interface, COVID mindset
New discoveries and innovations in science, politics, finance and culture that direct the course of our world are reported daily but rarely make it to the news. After years of research, scientific testing and peer-review, these novel ideas are published by the sharpest minds around the world in academic journals, which guide the world around us. In this podcast, we study the research papers, and bring you the transformative ideas so you stay sharp and prepared to make intelligent and timely decisions.Today's topics:1. Scientists develop a new method for identifying dreams during sleep from the electrical activity in the brain.2. New research shows certain types of traumatic experiences as a child can affect your brain size and cause brain thinning as adults.3. Is there a Marie Kondo gene that cleans up and organizes things in your body?4. Elon Musk reveals a new device that can link your brain directly to a computer, that he describes as a “Fitbit in your skull”.5. How to make decisions in the post-COVID era? Recent financial report discusses 4 ways to rethink about the future as we emerge from the COVID economic downturn.References 1. Lendner, J. D., Helfrich, R. F., Mander, B. A., Romundstad, L., Lin, J. J., Walker, M. P., ... & Knight, R. T. (2020). An electrophysiological marker of arousal level in humans. Elife, 9, e55092.2. Jenness, J. L., Peverill, M., Miller, A. B., Heleniak, C., Robertson, M. M., Sambrook, K. A., ... & McLaughlin, K. A. (2020). Alterations in neural circuits underlying emotion regulation following child maltreatment: a mechanism underlying trauma-related psychopathology. Psychological medicine, 1.3. Zavortink, M., Rutt, L. N., Dzitoyeva, S., Henriksen, J. C., Barrington, C., Bilodeau, D. Y., ... & Rissland, O. S. (2020). The E2 Marie Kondo and the CTLH E3 ligase clear deposited RNA binding proteins during the maternal-to-zygotic transition. Elife, 9, e53889.4. Neuralink LiveStream Accessed Aug 28 2020https://www.youtube.com/watch?v=sr8hzF3j2fo&feature=em-lbrm5. Strongin, S., Mirabal, D., The Great Reset: A Framework for investing after COVID-19, Goldman Sachs Researchhttps://www.goldmansachs.com/insights/pages/the-great-reset.html
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