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Anthony Waller works in oncology and talks about product management, the state of medical software, and his own personal battle with Leukemia.

Scott McNulty is a writer, podcaster, and director of communications for the IT department one of the top business schools in the world. He chats with Brett about documentation challenges, book writing, science fiction's commentary on society, and podcasting about Star Trek.

Jason Snell, prolific writer and podcaster, joins Brett to talk about long-term employment in the tech world, exploring job independence, 5K iMacs, and much more.

John Roderick guests to finish the tale of his musical career, complete with appearances by attractive people from in-flight magazines.

Virginia Roberts, online dating coach, stops by to talk about a world full of selfies, parenting decisions, and more.

Mike Rohde makes a return appearance to talk about writing, productivity, and his latest book, the Sketchnote Workbook.

Dr. Pam Peeke returns to systematic to discuss another type of addiction: technology addiction. How it's recognized, how it's treated, and who's at risk are all discussed, and there are some side trips involving German Shepherds. I forgot to ask what happens when she yells her dog's name at the park. I guess it depends on what kind of parks you go to. You'll get that after you listen. Maybe.

David Wain, writer, director and actor, makes a return appearance on Systematic to talk about the history of his work from The State to the present. Stella, Wet Hot American Summer, They Came Together, and more.

John Roderick returns for part 3 of his saga. Tune in to hear the tale of how the Long Winters musician got to where he is (almost) today.

Patrice Brend'amour has spent a lot of time studying Internet anonymity. He talks with Brett about that, as well as internationalizing Jekyll, doing a cooking show, and the Top 3 Picks, of course.

Brett's wife, Aditi, joins Systematic once again to talk about dog fighting, home automation, and Benedict Cumberbatch.

John Roderick makes a return appearance to continue the tale of his music career. Breaking up bands, accidental successes, and really, really long walks. Special cliffhanger ending... more to come.

Mike Rogers, elementary school principal, on trains, photography, and education.

Michael Simmons, co-founder of Flexibits and HockeyApp, stops by to talk about Fantastical, making it as an indie developer, the Tesla Model S and the real roots of capitalism.

David Sparks (MacSparky) stops by to chat about his new book and let Brett derail his train of thought whenever he can. Ella Fitzgerald and free-range organic eggs round out a fun episode.

In part one of what is going to be at least two episodes, John Roderick (musician, podcaster, you know who I'm talking about) tells the tale of how his music career started. It's a fascinating look at what was happening both inside his head and the context of the music scene around him.

Kevin Rothermel works in advertising and stops by to talk about "viral" marketing, Facebook advertising, emotional purchasing decisions, and standing desks, among other things.

Paul Gibbons, managing director and veterinarian of the Turtle Conservancy, talks about turtles (obviously), electric cars, and missing Minnesota.

Nat Osten, an iOS developer at Smile, joins Brett to discuss building for the sake of creation, stage fright, high school cafeterias, and the top picks of the week.