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Show Notes: https://eddyjoemd.com/hydrocortisone-cap/ Citation: Dequin PF, Meziani F, Quenot JP, Kamel T, Ricard JD, Badie J, Reignier J, Heming N, Plantefève G, Souweine B, Voiriot G, Colin G, Frat JP, Mira JP, Barbarot N, François B, Louis G, Gibot S, Guitton C, Giacardi C, Hraiech S, Vimeux S, L'Her E, Faure H, Herbrecht JE, Bouisse C, Joret A, Terzi N, Gacouin A, Quentin C, Jourdain M, Leclerc M, Coffre C, Bourgoin H, Lengellé C, Caille-Fénérol C, Giraudeau B, Le Gouge A; CRICS-TriGGERSep Network. Hydrocortisone in Severe Community-Acquired Pneumonia. N Engl J Med. 2023 Mar 21. doi: 10.1056/NEJMoa2215145. Epub ahead of print. PMID: 36942789. My website: ⁠www.eddyjoemd.com⁠ Instagram: ⁠www.instagram.com/eddyjoemd⁠ Twitter: ⁠www.twitter.com/eddyjoemd⁠ Facebook: ⁠www.facebook.com/eddyjoemd⁠ Podcast: ⁠https://anchor.fm/eddyjoemd⁠ My Amazon store for resources you may find helpful: ⁠www.amazon.com/shop/eddyjoemd --- Support this podcast: https://podcasters.spotify.com/pod/show/eddyjoemd/support

Show Notes: https://eddyjoemd.com/methylene-blue-septic-shock/ Link to Lactic Acid Post: https://eddyjoemd.com/lactic-acid-sepsis/ Citation: Ibarra-Estrada M, Kattan E, Aguilera-González P, Sandoval-Plascencia L, Rico-Jauregui U, Gómez-Partida CA, Ortiz-Macías IX, López-Pulgarín JA, Chávez-Peña Q, Mijangos-Méndez JC, Aguirre-Avalos G, Hernández G. Early adjunctive methylene blue in patients with septic shock: a randomized controlled trial. Crit Care. 2023 Mar 13;27(1):110. doi: 10.1186/s13054-023-04397-7. PMID: 36915146; PMCID: PMC10010212. Although great care has been taken to ensure that the information in this podcast are accurate, eddyjoe, LLC shall not be held responsible or in any way liable for the continued accuracy of the information, or for any errors, omissions or inaccuracies, or for any consequences arising therefrom. My website: www.eddyjoemd.com Instagram: www.instagram.com/eddyjoemd Twitter: www.twitter.com/eddyjoemd Facebook: www.facebook.com/eddyjoemd Podcast: https://anchor.fm/eddyjoemd My Amazon store for resources you may find helpful: www.amazon.com/shop/eddyjoemd --- Support this podcast: https://podcasters.spotify.com/pod/show/eddyjoemd/support

Show Notes: https://eddyjoemd.com/b12-septic-shock/ Citation: Patel JJ, Willoughby R, Peterson J, Carver T, Zelten J, Markiewicz A, Spiegelhoff K, Hipp LA, Canales B, Szabo A, Heyland DK, Stoppe C, Zielonka J, Freed JK. High-Dose IV Hydroxocobalamin (Vitamin B12) in Septic Shock: A Double-Blind, Allocation-Concealed, Placebo-Controlled Single-Center Pilot Randomized Controlled Trial (The Intravenous Hydroxocobalamin in Septic Shock Trial). Chest. 2023 Feb;163(2):303-312. doi: 10.1016/j.chest.2022.09.021. Epub 2022 Sep 26. PMID: 36174744. Although great care has been taken to ensure that the information in this podcast are accurate, eddyjoe, LLC shall not be held responsible or in any way liable for the continued accuracy of the information, or for any errors, omissions or inaccuracies, or for any consequences arising therefrom.     My website: www.eddyjoemd.com Instagram: www.instagram.com/eddyjoemd Twitter: www.twitter.com/eddyjoemd Facebook: www.facebook.com/eddyjoemd Podcast: https://anchor.fm/eddyjoemd My Amazon store for resources you may find helpful: www.amazon.com/shop/eddyjoemd --- Support this podcast: https://podcasters.spotify.com/pod/show/eddyjoemd/support

Show Notes: eddyjoemd.com/appreciating-nurses/ TrueLearn Link: https://truelearn.referralrock.com/l/EDDYJOEMD25/Discount code: EDDYJOEMD25 Citation: Vincent JL, Boulanger C, van Mol MMC, Hawryluck L, Azoulay E. Ten areas for ICU clinicians to be aware of to help retain nurses in the ICU. Crit Care. 2022 Oct 13;26(1):310. doi: 10.1186/s13054-022-04182-y. PMID: 36229859. Although great care has been taken to ensure that the information in this podcast are accurate, eddyjoe, LLC shall not be held responsible or in any way liable for the continued accuracy of the information, or for any errors, omissions or inaccuracies, or for any consequences arising therefrom.     My website: www.eddyjoemd.com Instagram: www.instagram.com/eddyjoemd Twitter: www.twitter.com/eddyjoemd Facebook: www.facebook.com/eddyjoemd Podcast: https://anchor.fm/eddyjoemd My Amazon store for resources you may find helpful: www.amazon.com/shop/eddyjoemd --- Support this podcast: https://podcasters.spotify.com/pod/show/eddyjoemd/support

Show Notes: eddyjoemd.com/clovers/ TrueLearn Link: https://truelearn.referralrock.com/l/EDDYJOEMD25/Discount code: EDDYJOEMD25 Citation: National Heart, Lung, and Blood Institute Prevention and Early Treatment of Acute Lung Injury Clinical Trials Network; Shapiro NI, Douglas IS, Brower RG, Brown SM, Exline MC, Ginde AA, Gong MN, Grissom CK, Hayden D, Hough CL, Huang W, Iwashyna TJ, Jones AE, Khan A, Lai P, Liu KD, Miller CD, Oldmixon K, Park PK, Rice TW, Ringwood N, Semler MW, Steingrub JS, Talmor D, Thompson BT, Yealy DM, Self WH. Early Restrictive or Liberal Fluid Management for Sepsis-Induced Hypotension. N Engl J Med. 2023 Jan 21. doi: 10.1056/NEJMoa2212663. Epub ahead of print. PMID: 36688507. --- Support this podcast: https://podcasters.spotify.com/pod/show/eddyjoemd/support

Show Notes: eddyjoemd.com/hello-2023/ --- Support this podcast: https://podcasters.spotify.com/pod/show/eddyjoemd/support

Evaluation of patients with Cardiogenic Shock. Why do we need a swan, introduction to CPO, PAPi and survival rates in these critically ill patients Show Notes: https://eddyjoemd.com/cardiogenic-shock-mcs/ TrueLearn Link: https://truelearn.referralrock.com/l/EDDYJOEMD25/Discount code: EDDYJOEMD25 --- Support this podcast: https://podcasters.spotify.com/pod/show/eddyjoemd/support

Evaluation of patients with Cardiogenic Shock. Part two of who knows how many episodes I will create on this topic. In this episode I discuss the stages and prognosis based on the staging. Show Notes: https://eddyjoemd.com/cardiogenic-shock-mcs/ TrueLearn Link: https://truelearn.referralrock.com/l/EDDYJOEMD25/ Discount code: EDDYJOEMD25 --- Support this podcast: https://podcasters.spotify.com/pod/show/eddyjoemd/support

Evaluation of patients with Cardiogenic Shock. Part one of who knows how many episodes I will create on this topic. Definition, Clinical Manifestations, Phenotypes and an Introduction to Management Strategies Show Notes: https://eddyjoemd.com/cardiogenic-shock-mcs/ TrueLearn Link: https://truelearn.referralrock.com/l/EDDYJOEMD25/ Discount code: EDDYJOEMD25 --- Support this podcast: https://podcasters.spotify.com/pod/show/eddyjoemd/support

How should we provide IV fluids to patient with acute pancreatitis? Let's look at a recent paper in the NEJM that helps with rate & duration. Show Notes: http://eddyjoemd.com/fluids-pancreatitis/ TrueLearn Link: https://truelearn.referralrock.com/l/EDDYJOEMD25/ Discount code: EDDYJOEMD25 Citation: de-Madaria E, Buxbaum JL, Maisonneuve P, García García de Paredes A, Zapater P, Guilabert L, Vaillo-Rocamora A, Rodríguez-Gandía MÁ, Donate-Ortega J, Lozada-Hernández EE, Collazo Moreno AJR, Lira-Aguilar A, Llovet LP, Mehta R, Tandel R, Navarro P, Sánchez-Pardo AM, Sánchez-Marin C, Cobreros M, Fernández-Cabrera I, Casals-Seoane F, Casas Deza D, Lauret-Braña E, Martí-Marqués E, Camacho-Montaño LM, Ubieto V, Ganuza M, Bolado F; ERICA Consortium. Aggressive or Moderate Fluid Resuscitation in Acute Pancreatitis. N Engl J Med. 2022 Sep 15;387(11):989-1000. doi: 10.1056/NEJMoa2202884. PMID: 36103415. --- Support this podcast: https://podcasters.spotify.com/pod/show/eddyjoemd/support

Should we use milrinone or dobutamine in patients in cardiogenic shock? NEJM published data providing us with the answer. Show Notes: https://eddyjoemd.com/milrinone-dobutamine/ TrueLearn Link: https://truelearn.referralrock.com/l/EDDYJOEMD25/ Discount code: EDDYJOEMD25 Citation: Mathew R, Di Santo P, Jung RG, Marbach JA, Hutson J, Simard T, Ramirez FD, Harnett DT, Merdad A, Almufleh A, Weng W, Abdel-Razek O, Fernando SM, Kyeremanteng K, Bernick J, Wells GA, Chan V, Froeschl M, Labinaz M, Le May MR, Russo JJ, Hibbert B. Milrinone as Compared with Dobutamine in the Treatment of Cardiogenic Shock. N Engl J Med. 2021 Aug 5;385(6):516-525. doi: 10.1056/NEJMoa2026845. PMID: 34347952. --- Support this podcast: https://podcasters.spotify.com/pod/show/eddyjoemd/support

Do Cardiogenic Shock Pts Need a Swan-Ganz/Pulmonary Artery Catheter? Let's look at the data. Let's also look at the devices such as pulse-contour analysis and bioreactance to see if they could replace the PA catheter in the management of cardiogenic shock. Show Notes: https://eddyjoemd.com/cardiogenic-shock-swan/ Mechanical Circulatory Support Notes: https://eddyjoemd.com/cardiogenic-shock-mcs/ --- Support this podcast: https://podcasters.spotify.com/pod/show/eddyjoemd/support

Pulmonary Artery Pulsatility Index (PAPi) is a hemodynamic parameter with prognostic value in pts w/right heart failure & cardiogenic shock. Show Notes: https://eddyjoemd.com/papi/ Citations: Lim HS, Gustafsson F. Pulmonary artery pulsatility index: physiological basis and clinical application. Eur J Heart Fail. 2020 Jan;22(1):32-38. doi: 10.1002/ejhf.1679. Epub 2019 Nov 28. PMID: 31782244. Škulec R, Parizek T, Stadlerova B, Bilska M, Cerny V. Subcostal TAPSE measured by anatomical M-mode: prospective reliability clinical study in critically ill patients. Minerva Anestesiol. 2021 Nov;87(11):1200-1208. doi: 10.23736/S0375-9393.21.15464-1. Epub 2021 May 13. PMID: 33982987. Modin D, Møgelvang R, Andersen DM, Biering-Sørensen T. Right Ventricular Function Evaluated by Tricuspid Annular Plane Systolic Excursion Predicts Cardiovascular Death in the General Population. J Am Heart Assoc. 2019 May 21;8(10):e012197. doi: 10.1161/JAHA.119.012197. PMID: 31088196; PMCID: PMC6585329. Korabathina R, Heffernan KS, Paruchuri V, Patel AR, Mudd JO, Prutkin JM, Orr NM, Weintraub A, Kimmelstiel CD, Kapur NK. The pulmonary artery pulsatility index identifies severe right ventricular dysfunction in acute inferior myocardial infarction. Catheter Cardiovasc Interv. 2012 Oct 1;80(4):593-600. doi: 10.1002/ccd.23309. Epub 2012 Jan 10. PMID: 21954053. Morine KJ, Kiernan MS, Pham DT, Paruchuri V, Denofrio D, Kapur NK. Pulmonary Artery Pulsatility Index Is Associated With Right Ventricular Failure After Left Ventricular Assist Device Surgery. J Card Fail. 2016 Feb;22(2):110-6. doi: 10.1016/j.cardfail.2015.10.019. Epub 2015 Nov 10. PMID: 26564619. Kang G, Ha R, Banerjee D. Pulmonary artery pulsatility index predicts right ventricular failure after left ventricular assist device implantation. J Heart Lung Transplant. 2016 Jan;35(1):67-73. doi: 10.1016/j.healun.2015.06.009. Epub 2015 Jun 17. Erratum in: J Heart Lung Transplant. 2017 Nov;36(11):1272. PMID: 26212656. Kapur NK, Esposito ML, Bader Y, Morine KJ, Kiernan MS, Pham DT, Burkhoff D. Mechanical Circulatory Support Devices for Acute Right Ventricular Failure. Circulation. 2017 Jul 18;136(3):314-326. doi: 10.1161/CIRCULATIONAHA.116.025290. PMID: 28716832. --- Support this podcast: https://podcasters.spotify.com/pod/show/eddyjoemd/support

Should we provide our DKA patients with sodium bicarbonate (bicarb) pushes or drips to improve their pH? Let's look at the data. Show Notes: https://eddyjoemd.com/bicarb-dka/ --- Support this podcast: https://podcasters.spotify.com/pod/show/eddyjoemd/support

When you're taking one of those automated blood pressure measurements on an oscillometric device, you should trust the MAP. Show Notes: https://eddyjoemd.com/oscillometric-map/ --- Support this podcast: https://podcasters.spotify.com/pod/show/eddyjoemd/support

The European Respiratory Society has provided 8 conditional recommendations for the use of nasal high flow/high flow nasal cannula/high flow oxygen/whatever you want to call it. Here, I review the 8 recommendations and add some commentary on them.  Show Notes: https://eddyjoemd.com/high-flow/ Citation: Oczkowski S, Ergan B, Bos L, Chatwin M, Ferrer M, Gregoretti C, Heunks L, Frat JP, Longhini F, Nava S, Navalesi P, Ozsancak Uğurlu A, Pisani L, Renda T, Thille AW, Winck JC, Windisch W, Tonia T, Boyd J, Sotgiu G, Scala R. ERS clinical practice guidelines: high-flow nasal cannula in acute respiratory failure. Eur Respir J. 2022 Apr 14;59(4):2101574. doi: 10.1183/13993003.01574-2021. PMID: 34649974. --- Support this podcast: https://podcasters.spotify.com/pod/show/eddyjoemd/support

Is intermittent fasting (time-restricted-eating) with a calorie restriction better than just a calorie restriction?  Show Notes: https://eddyjoemd.com/intermittent-fasting/ Citation: Liu D, Huang Y, Huang C, Yang S, Wei X, Zhang P, Guo D, Lin J, Xu B, Li C, He H, He J, Liu S, Shi L, Xue Y, Zhang H. Calorie Restriction with or without Time-Restricted Eating in Weight Loss. N Engl J Med. 2022 Apr 21;386(16):1495-1504. doi: 10.1056/NEJMoa2114833. PMID: 35443107. --- Support this podcast: https://podcasters.spotify.com/pod/show/eddyjoemd/support

Aspirin has been thoroughly studied for patients with COVID-19. This study is a positive trial suggesting benefits to using it. But should we? Let's interpret the data given recent advancements.  Show Notes: https://eddyjoemd.com/aspirin-covid/ Although great care has been taken to ensure that the information in this podcast are accurate, eddyjoe, LLC shall not be held responsible or in any way liable for the continued accuracy of the information, or for any errors, omissions or inaccuracies, or for any consequences arising therefrom. Citation: Hawkins K, Jackson AM, Quintana MT, Lankford AS, Keneally RJ, Al-Mashat M, Fisher D, Williams J, Berger JS, Mazzeffi MA, Crandall KA; N3C Consortium and ANCHOR Investigators. Association of Early Aspirin Use With In-Hospital Mortality in Patients With Moderate COVID-19. JAMA Netw Open. 2022 Mar 1;5(3):e223890. doi: 10.1001/jamanetworkopen.2022.3890. PMID: 35323950; PMCID: PMC8948531. --- Support this podcast: https://podcasters.spotify.com/pod/show/eddyjoemd/support

In patients who are immunocompromised, we must determine whether using high flow oxygen (HFNC/NHF/HFO) or NIV would better serve our patients Show Notes: https://eddyjoemd.com/high-flow-immunocompromised/ Although great care has been taken to ensure that the information in this podcast are accurate, eddyjoe, LLC shall not be held responsible or in any way liable for the continued accuracy of the information, or for any errors, omissions or inaccuracies, or for any consequences arising therefrom. Citation: Bourenne J, Girault C, Vinsonneau C, Dellamonica J, Labro G, Jochmans S, Herbland A, Quenot JP, Devaquet J, Benzekri D, Vivier E, Nseir S, Colin G, Thevenin D, Grasselli G, Bougon D, Assefi M, Guérin C, Lherm T, Kouatchet A, Ragot S, Thille AW; FLORALI-IM study group and the REVA Research Network. High-flow nasal oxygen alone or alternating with non-invasive ventilation in critically ill immunocompromised patients with acute respiratory failure: a randomised controlled trial. Lancet Respir Med. 2022 Mar 21:S2213-2600(22)00096-0. doi: 10.1016/S2213-2600(22)00096-0. Epub ahead of print. PMID: 35325620. --- Support this podcast: https://podcasters.spotify.com/pod/show/eddyjoemd/support

Should we be considering tPA (alteplase) as a last-ditch effort to try to improve oxygenation in our COVID-19 patients? Show Notes: https://eddyjoemd.com/tpa-covid/ Although great care has been taken to ensure that the information in this podcast are accurate, eddyjoe, LLC shall not be held responsible or in any way liable for the continued accuracy of the information, or for any errors, omissions or inaccuracies, or for any consequences arising therefrom. Citation: Barrett CD, Moore HB, Moore EE, Wang J, Hajizadeh N, Biffl WL, Lottenberg L, Patel PR, Truitt MS, McIntyre RC Jr, Bull TM, Ammons LA, Ghasabyan A, Chandler J, Douglas IS, Schmidt EP, Moore PK, Wright FL, Ramdeo R, Borrego R, Rueda M, Dhupa A, McCaul DS, Dandan T, Sarkar PK, Khan B, Sreevidya C, McDaniel C, Grossman Verner HM, Pearcy C, Anez-Bustillos L, Baedorf-Kassis EN, Jhunjhunwala R, Shaefi S, Capers K, Banner-Goodspeed V, Talmor DS, Sauaia A, Yaffe MB. Study of Alteplase for Respiratory Failure in SARS-CoV-2 COVID-19: A Vanguard Multicenter, Rapidly Adaptive, Pragmatic, Randomized Controlled Trial. Chest. 2022 Mar;161(3):710-727. doi: 10.1016/j.chest.2021.09.024. Epub 2021 Sep 27. PMID: 34592318; PMCID: PMC8474873. --- Support this podcast: https://podcasters.spotify.com/pod/show/eddyjoemd/support