45 minutes | Jul 6th 2020

Episode 149: A Biomarker to Predict MS Progression with Dr. Robert Fox and Caroline Sincock

Play Next
Mark Played
The International Progressive MS Alliance is about to publish a paper that recommends advancing research on a specific biomarker to predict MS progression, and we're getting a pre-publication preview of what that paper is all about.   My guests are Dr. Robert Fox, a neurologist and Vice-Chair for Research at the Cleveland Clinic Neurological Institute, and Caroline Sincock, who lives with progressive MS. Both Doctor Fox and Caroline are members of the International Progressive MS Alliance Scientific Steering Committee and are among the authors of the new paper that we're going to preview.      We're also talking about the results of a study that show how increasing the energy in cells damaged by demyelination may stop MS progression.   We'll tell you why Mayzent failed to gain approval to treat active secondary progressive MS in England. We'll introduce you to the winner of the first Novartis Innovation Prize for Assistive Tech for Multiple Sclerosis. And we'll discuss study results that show that a protein in the blood called neurofilament light chain may predict MS progression.   We have a lot to talk about! Are you ready for RealTalk MS??!

The 2020 ACTRIMS-ECTRIMS Virtual Conference  3:10

Boosting cellular energy at sites of myelin loss may stop MS progression  4:18

Why NICE failed to approve Mayzent to treat active secondary progressive MS    6:29

Novartis Innovation Prize awarded to AccessNow  9:04

Elevated neurofilament light chain may predict risk of MS progression  10:02

My Interview with Dr. Robert Fox and Caroline Sincock  11:27

Share this episode  42:11

Please Support the National MS Society COVID-19 Response Fund  42:30


Just copy this link & paste it into your text or email:  https://realtalkms.com/149


I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts!

Email: jon@realtalkms.comPhone: (310) 526-2283

And don't forget to join us in the RealTalk MS Facebook group!


If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com

National MS Society's Ask An MS Expert Video Replay

What You Need to Know About Coronavirus (COVID-19)

National MS Society COVID-19 Response Fund

International Progressive MS Alliance

STUDY: Enhanced Axonal Response of Mitochondria to Demyelination Offers Neuroprotection: Implications for Multiple Sclerosis


STUDY: Plasma Neurofilament Light Levels are Associated with Risk of Disability in Multiple Sclerosis

Join the RealTalk MS Facebook Group

Download the RealTalk MS App for iOS

Download the RealTalk MS App for Android

Give RealTalk MS a Rating and Review

Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com.

RealTalk MS Episode 149 Hosted By: Jon Strum Guests: Dr. Robert Fox and Caroline Sincock

Tags: MS, MultipleSclerosis, MSResearch, MSSociety, RealTalkMS

Privacy Policy

Play Next
Mark Played