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59 minutes | Aug 10, 2022
5.07 - Plenary Session Alps Edition
Timothee Olivier joins me to discuss recent papers: IMPOWER10 Checkmate 816 Path CR/ EFS/ Surrogates Drug Dosing, cGCSF rules and more Bread and butter oncology
31 minutes | Jul 21, 2022
5.06 - POLO trial now has OS results - OMG
The POLO trial, which we first broke on PS Season 1- is back with null OS results. But the trial authors enter the spin cycle. VP goes line by line.
37 minutes | Jul 18, 2022
5.05 - Citations, Metrics, Rankings in Oncology & Medicine
VP explains H index, total cites, papers, US News and World Report rankings and how evaluates researchers and doctors.
39 minutes | Jul 14, 2022
5.04 - Echelon 1 reports OS benefit - But does it add up?
VP addresses what to do you if you get an idea from listening to the show, and deconstructs ECHELON-1. Instead of listening we highly recommend you watch the video on YouTube with graphics. This is worth the watch.
51 minutes | Jul 13, 2022
5.03 - VPs Grand Rounds Lecture - Evidence Based Medicine - Will it Survive?
How to think about when and how to do RCTs? What are the limitations to observational studies? Smoking. Parachutes. Dostarlimab. Guarantee Time Bias. Confounding. Multiple Hypothesis testing and more
47 minutes | Jul 11, 2022
5.02 - Listener Questions - Cancer & Evidence Philosophy - What this Pod Offers
I make the case why this podcast should be your go to for Med, Onc & Policy. I describe my philosophy of Evidence, Empiricism, and show how this connects to many oncology studies. I answer a bunch of Listener Questions
38 minutes | Jul 7, 2022
5.01 - How To Read Randomized Trials In Cancer
How to read randomized trials in cancer medicine. Phase 2 vs 3, control arm, crossover, post protocol, censoring (the basics), and how law professors and medical professors are different and why it matters.
19 minutes | Jun 22, 2022
Lies and Exaggerations about Kids Vaccines < 5 years Old is Bad Public Health
Lies and Exaggerations about Kids Vaccine I give examples, and show why they are lies
15 minutes | Jun 20, 2022
Enact Trial - Enza vs Active Surveillance in Localized Prostate Cancer
What happens when you treat people with $168,000 a year medicine when most of them will never need treatment, and all of them don't need treatment now
43 minutes | Jun 18, 2022
Kids Vaccine For Under 5 years Old
I take a deep dive into the data for the mRNA vaccines for kids under 5 years olds
77 minutes | Jun 18, 2022
H. Jack West; Lung Cancer; Podcasting; TeleHealth: PACIFIC; ADAURA;CM816: KN189
I sit down with H Jack West. City of Hope. Thoracic Oncology and we have a long discussion about trials; staging; PDL1 thresholds; Driver mutations and post protocol care; ADAURA; Adjuvant; & More
42 minutes | Jun 15, 2022
QuANTUM - Quizartinib Front Line - Ethics of Global Trials
I discuss the timeline of Ratify and Quantum. Was this an ethical trial? Is it sufficient to say a trial is ethical because 50% of participants get something?
38 minutes | Jun 9, 2022
4.67 Teclistimab for R/R Multiple Myeloma
The drug has a high response rate and lots of infections, is it active? Yes; Efficacious? ???? I review ASCO2022 updates
24 minutes | Jun 8, 2022
4.66 PD1 Ab for MSI H Stage II/ III Rectal Cancer; A 100% CR rate??
Are the results from Luis Diaz as good as touted. What trial should they do going forward? A 100% CR rate in Stage II and III rectal cancer??
32 minutes | Jun 7, 2022
4.65 DESTINY BREAST 04 - A complex trial to deconstruct
My take on the standing ovation for DESTINY Breast 04 Traztuzumab Deruxtecan vs. Investigator choice after endocrine therapy and 1 or 2 chemotherapies for HER2 low
32 minutes | Jun 6, 2022
4.64 - DETERMINATION - Should we still use transplant Myeloma?
I break down Richardson, et al. NEJM DETERMINATION Transplanters are determined to keep going, should they be? Watch the videos b/c I have lots of great visuals My ASCO Coverage continues
35 minutes | Jun 5, 2022
4.63 - ASCO22 - DYNAMIC - Can CT DNA Allow us to Give Less Chemo in Stage II Colon Cancer
The second paper from #ASCO2022 #ASCO22 that I break down This is one of the most technical papers I breakdown on the channel CT DNA used to omit chemo in Stage II colon cancer Read the book Malignant if you learn from this Watch the YouTube Figures https://youtu.be/QxOBIi7I2BU
18 minutes | Jun 4, 2022
4.62 - SHINE - Ibrutinib BR vs BR; Limitations to the trial
Continuous vs. Fixed, 3 vs 2, PFS is the primary endpoint No OS Bad crossover Lots to discuss here I will be covering all the major ASCO papers on @PlenarySession Subscribe to my substack https://vinayprasadmdmph.substack.com/
55 minutes | May 27, 2022
4.61 - How CDC's Vaccine Safety Missed Cases Of Myocarditis
I am joined by Dr. Katie Sharff, infectious disease doc, to discuss two of her papers on myocarditis after COVID-19 vaccination. https://doi.org/10.1016/j.amjcard.2022.02.039 https://doi.org/10.1101/2021.12.21.21268209
34 minutes | May 21, 2022
4.60 - NEW JCO paper - AML, EFS, CR, CRi, and Surrogate validation - FDA & Methods
I get back to my roots; I explain surrogate validation and a new JCO paper from the FDA authors on EFS and OS in AML. You won't want to miss it
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