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Molecular Moments Podcast
59 minutes | Sep 24, 2021
Charles Sabine: Huntington's Disease, Gene Therapy, and Hope
Chad Briscoe and Jim McNally talk with Emmy-winning journalist and producer Charles Sabine on this episode of Molecular Moments. Their discussion centers around rare diseases, gene therapy and Huntington's Disease (HD). Charles, a carrier of the HD gene who has lost several immediate family members to the disease, is an ardent advocate for patients and families suffering from rare degenerative diseases. From covering war zones to becoming a gene therapy patient, they discuss Charles’ career with MSNBC, his subsequent coverage of the Bosnian War, and his Emmy-winning coverage of the Romanian revolution. He also shared about his family’s medical issues, including his discovery that his father, uncle, and brother were all HD gene carriers. His father was one of the first people to be tested genetically for the disease in 1993. Jim, Chad, and Charles discuss the possibility of gene therapies halting further disease development rather than doctors prescribing drugs for a lifetime. Additionally, the trio discuss the boom in gene therapies, the pros and cons of genetic testing, and how rare disease patients are generally underserved in the biotech industry. See omnystudio.com/listener for privacy information.
32 minutes | Aug 20, 2021
Dr. Jennifer Zemo talks mentorship, kinase proteins and customer service!
On this episode of Molecular Moments, Chad Briscoe chats with Dr. Jennifer Zemo, Director, Bioanalytical Operations at BioAgilytix. She’s a great leader, mentor and scientist with a love for helping people and the sciences. They discuss her start as a chemistry major in college, which led to her Ph.D. in Biological Chemistry and eventually to joining BioAgilytix 8 years ago. A large molecule expert, Jennifer shares how she went from pharma to CRO, the importance of customer service and the ability to be creative in assay development. They also discuss how company culture shifted during the COVID pandemic, the first place she would like to visit after things go back to normal and what motivates her. See omnystudio.com/listener for privacy information.
57 minutes | Jun 18, 2021
Dr. Afshin Safavi talks about creating BioAgilytix, Hot Yoga and Rap Music!
In this episode of Molecular Moments, Chad talks with Dr. Afshin Safavi, a bioanalytical thought leader, BioAgilytix founder, and board member. Afshin shares how his interest in the sciences was sparked by his mother's perfumes and household items, and how he went from pursuing a career in electronic engineering to dentistry and then into pharmaceuticals! They also discuss Afshin’s upcoming children's book, the value of mentorship, trying new things like hot yoga, and his future as a rap artist.See omnystudio.com/listener for privacy information.
48 minutes | May 28, 2021
Jeff Sutherland Discusses Dogs: Canine Nutrition and Oncology Advances
In this episode, Chad sits down with Jeff Sutherland, founder and CEO of Canine Biologics. With over 500,000 dogs in the US and Canada diagnosed with cancer each year, Jeff’s company addresses nutritional needs for dogs to fight terminal diseases based on tumor type. They discuss how Jeff started off as pre-med in college before shifting his focus to marketing, then to dental technology, and finally to IT with a master's in Artificial Intelligence before realizing his true passion…the health of dogs. Jeff shares how he was able to fulfill a dream of living in New Zealand thanks to an IT skill shortage at the time and how his dog inspired him to make the career change of creating restaurant-quality dog food with the proper nutrients that dogs need, and how an oncology vet inspired him to take a leap to create Canine Biologics. They end with a chat about travel bucket lists including the lakes region in Italy near Switzerland, Patagonia in South America, New Zealand, and Japan.See omnystudio.com/listener for privacy information.
46 minutes | May 7, 2021
Drs. Jolly Mazumdar and Tim Chendrimada: Dreaming Big, Coffee Beans and Self Amplifying RNA
In today's episode, Chad sits down with guest scientists, Drs. Jolly Mazumdar and Tim Chendrimada, CEO, and CSO of Chimeron Bio. Two different beginnings; one in the sciences studying bugs and infectious diseases and the other in agriculture, specifically coffee beans! They talk to Chad about how their very different paths led them to become a dynamic duo in the next generation of RNA therapeutics. From Tim asking a scientist of Wistar Institute to take a chance on him with no prior experience in medical science to Jolly traveling to the United States for graduate studies in infectious diseases, we learn about how the pair, originally from India, carved their paths to where they are now as veterans in the Pharma industry. Both with careers early on at GlaxoSmithKline (GSK), Jolly’s focus was on biomarkers and innovative early clinical trials in skin cancer drugs and Tim’s on the development side as a bench scientist and the importance of having teamwork when it comes to drug development. These valuable experiences led them to create Chimeron Bio. They talk about how the opportunity to create Chimeron Bio came to be, the importance of challenging yourself and taking risks you believe in, talking to investors, their technology pipeline and self-amplifying RNA COVID-19 vaccine that protects against new variants. See omnystudio.com/listener for privacy information.
46 minutes | Apr 16, 2021
Dr. John Smeraglia Talks Globe Trotting, Italian Food and Magnetic Sector Mass Spectrometers!
In today's episode, Chad sits down with guest scientist, Dr. John Smeraglia, Vice President & Head of Translational Biomarkers and Bioanalysis at UCB. John is an experienced pharma leader in the development and service side of the industry. John talks to Chad about his experiences working in the UK, such as picking up basketball and taking apart a massive magnetic sector mass spectrometer in his early days of working in bioanalysis. They also discuss John’s transfer to San Diego, California, the language barriers encountered while working in Belgium and building a diagnostic PCR laboratory in two weeks as a response to a need in Belgium during the COVID pandemic. Chad and John also delve into other important topics such as Bon Jovi vs. Springsteen, favorite Italian food, and most importantly, life mottos.See omnystudio.com/listener for privacy information.
43 minutes | Mar 19, 2021
Angela Stoyanovitch talks Detroit Pride, Legal Drugs, and the Google of CROs
In today’s episode, Chad sits down with Angela Stoyanovitch, a director of business development at BioAgilytix and founder of the Legal Drugs podcast. She’s a podcaster, veteran business developer, social media strategist and consultant who kicked off her career in research who has held business development roles across pre-clinical research, bioanalysis and in basic research. They discuss how she fell in love with the service side of research and her advice for others interested the drug industry.See omnystudio.com/listener for privacy information.
43 minutes | Feb 26, 2021
Dr. Laura Sepp-Lorenzino Talks Gene Editing, Mentorships, and Making Big Moves!
In today’s episode, Chad sits down with guest scientist, Dr. Laura Sepp-Lorenzino the Chief Scientific Officer at Intellia Therapeutics. Laura is an innovative leader in drug discovery and the development of small molecules and nucleotide therapeutics. Pharma is in Laura’s blood as her mother, a pharmacist, encouraged her to pursue a career in the science. She shares how she went from studying biochemistry in Argentina and her pursuit of a Ph.D., then pivoting in a life-changing move to the United States. She also talks about the importance of paying it forward as a mentor, how gene therapy can prevent diseases, gene editing at Intellia Therapeutics, debunking stigmas behind vaccines, revisiting the Rubik’s Cube, and joining a debate club!See omnystudio.com/listener for privacy information.
50 minutes | Dec 29, 2020
Dr. Tina Morris Talks Photography, Bioanalytics and Leadership!
In today’s episode, Chad sits down with guest scientist, Dr. Tina Morris the executive director of the AAPS. Tina has a distinguished career in the pharmaceutical industry including senior leadership roles at US Pharmacopia, Parenteral Drug Association, and the AAPS. She helps us understand the importance of these industry organizations and how we can make a difference by getting involved. She brings real credibility as a scientist in her leadership roles as we hear about her experiences as a senior-level scientist at Ciphergen and Human Genome Sciences. They also talk about highlights of science from 2020 and beyond...talking science as scientists do. See omnystudio.com/listener for privacy information.
36 minutes | Dec 28, 2020
Mike Mortimer Talks Brexit, Biking and Business!
In today’s episode, Chad sits down with guest Mike Mortimer, co-founder, and partner of London-based GHO Capital. Mike has had a distinguished career in healthcare including senior leadership roles at Quintiles, board positions with numerous healthcare companies including BioAgilitx, and for the last six years with GHO Capitals. At Quintiles he was a part of the team that grew the company to be the dominant late-stage CRO in the industry and now at GHO Capital, his team directs funding to build the future of healthcare with a focus on European investments. They chat about the business side of the pharmaceutical industry, his thoughts on Brexit, and biking over 2,000 miles! See omnystudio.com/listener for privacy information.
37 minutes | Nov 13, 2020
Dr. Marianne Fjording talks biomarkers, CROs, and tomatoes!
In today’s episode, Chad sits down with guest scientist and biomarker expert, Dr. Marianne Fjording (Scientific Officer, BioAgilytix). Marianne and Chad discuss her expertise in biomarkers and EU bioanalysis- including how Denmark became a scientific hub and what fit-for-purpose really means. They also dive into Marianne’s jump from pharma to CRO, a family trip gone wrong, and how she ended up with over 100 varieties of tomatoes during the COVID quarantine.See omnystudio.com/listener for privacy information.
29 minutes | Oct 19, 2020
Dr. Jim McNally Talks Gene Therapy, Superheroes and Celery!
Welcome to episode one of the Molecular Moments podcast! On this first episode, Dr. Chad Briscoe is joined by his guest, PhD scientist, Dr. Jim McNally, and they get down to business as the two explore the various nuances in the outstanding work of McNally, how his career in bioanalysis became personal in an unexpected way, and what type of gene therapy it would take to create the next Superman or Hulk! They also discuss: How bioanalysis has evolved within the gene therapy space and how it has the ability to treat patients who are suffering from cancer or diseases Dr. McNally’s passion and curiosity for immunogenicity Unraveling immunogenetic data for drug development Developing drugs for gene therapy and problem-solving as a program lead Whether gene therapy realistically has the potential to create superheroes How Dr. McNally’s mentors, like Dr. Boris Gorovitz, while at Pfizer, helped him grow to become a better scientist. And why he thinks it’s important for him to mentor other scientists. His son’s Crohn's disease diagnosis and balancing being both a father and bioanalytical scientist while seeing first-hand the benefits of biotherapies. And Dr. McNally’s passion for…celery! Did you enjoy this episode? Be sure to subscribe and rate Molecular Moments on Apple or anywhere else you get your podcasts! See omnystudio.com/listener for privacy information.
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