You Should Measure the Length of Your Critically-Short Telomeres – EP19: Stephen Matlin (Life Length)
In this nineteenth episode, Stephen Matlin introduces telomere biology. He details how testing services typically use Q-PCR which provides an average telomere length and why that doesn’t really mean anything.
Read the transcript
Instead the percentage of critically-short, measured using Q-FISH, does. Finally he chats about supplements – telomerase inducers – for growth.
Topics we discussed in this episode
Introduction to telomere biology
Hayflick limit, senescent cells, apoptosis
Telomeres and the hallmarks of aging
Quantitative PCR derived average telomere length vs shortest telomeres
Coefficient of variation of lab samples
Role of supplements in supporting our telomeres and overall biological function
Declining nutrition in even vegetables
Telomerase inducers TA-65 and TAM-818
Telomerase enzyme
Henrietta Lacks cells, cancer and the Hayflick limit
Telomerase supplements and cancer
Telomerase inducer Telomere Benefits
Providing biological age scores using telomere measurements
Telomere length and correlation with healthspan
Improving upon biomarker Prostate Specific Antigen with Prostate Telomere Associate Variance
Show links
LifeLength.com
T.A. Sciences TA-65
T.A. Sciences TA-65
Hayflick, His Limit, and Cellular Ageing
The Hayflick Limit
The End-Replication Problem
Leucocyte Telomere Length And Risk Of Cardiovascular Disease: Systematic Review And Meta-analysis
Association Between Leucocyte Telomere Length And Cardiovascular Disease In A Large General Population In The United States
The Hallmarks of Aging
Coefficient of Variation
A Natural Product Telomerase Activator Lengthens Telomeres in Humans: A Randomized, Double Blind, and Placebo Controlled Study
The Telomerase Activator Ta-65 Elongates Short Telomeres And Increases Health Span Of Adult/old Mice Without Increasing Cancer Incidence
Discovery Of Potent Telomerase Activators: Unfolding New Therapeutic And Anti-aging Perspectives
The Nobel Prize in Physiology or Medicine 2009
Defy Time
Telomere Benefits
Mathematical Connection Between Short Telomere Induced Senescence Calculation And Mortality Rate Data
Comparison Of Telomere Length Measurement Methods
Beyond Average: Potential For Measurement Of Short Telomeres
The post You Should Measure the Length of Your Critically-Short Telomeres – EP19: Stephen Matlin appeared first on Quantified Health, Wellness & Aging Podcast.
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