Listen Now

Artificial Intelligence was once the realm of science fiction. But over the last several years, advances in machine learning and deep neural networks have moved us closer to a reality where computers can learn and solve problems independently, the way a human does. From art and music to medicine and politics, the potential applications of AI are nearly endless, and the technology just keeps getting better. This week on How I Built This Lab, Guy talks with one of the leaders in the field of AI development, Sam Altman. Sam talks about his journey from Stanford dropout and teenage entrepreneur to president of the legendary startup incubator Y Combinator and co-founder of the nonprofit OpenAI. Plus, Sam shares his hopes and fears for the future of AI and how his company is working to ensure it ultimately benefits all of humanity. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Obsessed with TV and passionate about writing, Issa Rae sent an unsolicited script to CBS’s Cosby when she was still in middle school. By her 20's, she realized there was a certain type of character that was absent from the media landscape—a character she would eventually inhabit in her breakout YouTube series, "Mis-Adventures of Awkward Black Girl." From there, Issa created the five-season HBO hit Insecure, but first went through a bruising gauntlet of rejections and reversals as she learned to navigate Hollywood. Today, Issa has built a company—HOORAE Media—which produces her new HBO show, Rap Sh!t, and multiple other TV and film projects.  Listen to The Great Creators launching September 20th See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Picture this: you just wrapped a long day of work and you are starving! You open a delivery app and place an order from your favorite restaurant. About an hour later, you get a notification that your meal has arrived. You’re practically salivating as you tear open the bag, and then...a rude awakening — your dinner became cold and soggy in transit.  This frustrating and all-too-common experience is exactly what Marc Lore is trying to solve with his latest venture, Wonder. This week on How I Built This Lab, Marc returns to the show to share how Wonder, recently valued at $3.5 billion, has the potential to disrupt the entire food delivery and home dining industry. Plus, Marc offers advice on how to approach big challenges and discusses several other business ideas he’s been cooking up since leaving Walmart last year. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

The Great Creators with Guy Raz premieres on September 20th, featuring conversations about creativity with some of the most celebrated actors, musicians and performers of our time. Each week, Guy sits down with notable and beloved entertainers to trace their life’s journey, dive deep into their work, and illuminate the source of their creativity. With each episode you’ll have a true appreciation for how your favorite creators found greatness, and might even feel inspired to ignite your own creativity. In a recent episode, Guy interviewed actor, comedian and talk show host Stephen Colbert. They talked about Colbert’s journey, from his early days doing stand-up in Chicago to taking the coveted late-night gig at CBS, and how each experience helped sculpt him into the legend we know today, and his source of creativity throughout it all. Listen to The Great Creators with Guy Raz: wondery.fm/tgc-hibt See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

David Heath and Randy Goldberg saw an opportunity to disrupt a long dormant—and arguably boring sector...socks. They met at a startup in their 20s, each already had their own side hustles before they hatched a plan to launch a business together. Randy and David didn’t initially intend to get into the sock business, but in 2011, David read that socks are the most requested clothing item at homeless shelters. That led them to start a company they called Bombas based on a promise: for each pair of socks a customer bought, another would be donated to the homeless. Within about ten years, their one-for-one start-up turned into a quarter of a billion dollar business that has expanded into sweatshirts, underwear, and t-shirts. Listen to The Great Creators launching September 20th See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Water is all around us–quite literally, there is enough water in the air we breathe to meet all of humanity’s needs and then some. Engineering professor Cody Friesen invented a solar-powered device that captures this vapor and transforms it into drinking water. Cody began manufacturing these ‘hydropanels’ with his Arizona-based company SOURCE in 2014, and today they’re used in more than 50 countries worldwide. This week on How I Built This Lab, Cody talks with Guy about the prevalence of water scarcity in the U.S. and around the globe, and his company’s work to become the world’s first renewable, fully-digitized drinking water utility. Plus, the two discuss how entrepreneurs should be thinking about the growing renewable energy market. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

When you consider the risk of doing business, it doesn’t get much bigger than starting a car company: competition is formidable, startup costs are in the billions, and very few people believe you can pull it off. That’s the massive challenge RJ Scaringe walked into in 2009, when he launched his truck and SUV company, Rivian. To add to the risk, RJ wanted to build fully electric vehicles while attracting drivers who’d never bought them, so he knew his trucks had to be fun and sporty: appealing in their own right. Rivian’s journey has taken RJ from an old warehouse in Florida to a massive Midwestern car manufacturing plant; and from years of stealth planning to months of anticipatory buzz from buyers and the industry. Rivian rolled its first trucks off the line in 2021, and is hustling to fulfill tens of thousands of vehicle reservations from excited customers. There have been pivots, sleepless nights, and, of course, multiple supply chain issues, but today, Rivian is valued at $30 billion and is a major player in the electric vehicle industry. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

On October 9, 2012, Shiza Shahid’s life changed forever. It was on that day that 15-year-old Pakistani activist Malala Yousafzai was shot in the head by a Taliban gunman, capturing the world’s attention. Before long, 22-year-old Shiza found herself leaving her corporate job to join a recovering Malala and her father in launching the Malala Fund, a nonprofit that advocates for girls’ education across the globe.  Little did Shiza know, this venture was actually just the beginning of her entrepreneurial journey... This week on How I Built This Lab, Shiza recounts the childhood experiences that forged her commitment to public service and advocacy—ultimately shaping her worldview and leading to her first encounter with Malala. She also discusses her pivot to the for-profit world with Our Place, the cookware company she co-founded in 2019 that’s both profitable and making an impact. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In 2009, Sarah Kauss had a well-paying job in real estate development, but she was itching to do something more. On a hike in Tucson with her mom, she got an idea for a business while swigging warm water from a metal thermos: Why not design a water bottle that kept cold things cold and hot things hot, but was also beautiful to look at? Just six years after launch, S'well reportedly made $100 million, and today, Sarah is especially focused on how the brand can help eliminate plastic waste around the world. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

You might not expect a deep friendship to bloom from an argument about favorite authors...in a Miami bar...during spring break. Yet that’s exactly how Greg Solano and Wylie Aronow’s long journey to becoming business partners began...  Fast forward more than a decade, and Greg and Wylie are now co-founders of Yuga Labs—the company behind the Bored Ape Yacht Club NFT collection. Since the collection was unveiled in spring 2021, the value of each digital ape has skyrocketed, with celebrities like Paris Hilton, Snoop Dog and Madonna getting in on the action. Within a year of its founding, Yuga Labs received a whopping $4 billion valuation, making it one of the fastest companies ever to achieve unicorn status.  This week on How I Built This Lab, Greg and Wylie recount their whirlwind success story in one of their first-ever public interviews. We hear how a shared love of storytelling and online gaming helped spawn the idea for the bored apes; plus, Greg and Wylie tell Guy about the next big endeavor for Yuga Labs: expanding into the metaverse. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In 1970, George Zimmer was a college graduate with no real job prospects and little direction. That's when his father, an executive at a boy's clothing company, asked him to go on an important business trip to Asia. It was that trip that propelled him into the world of men's apparel. In 1973, the first Men's Wearhouse opened in Houston with little fanfare, but by the mid-80s, George Zimmer managed to carve out a distinct niche in the market—a place where men could buy a good quality suit, at "everyday low prices," along with all the shirts, ties, socks, and shoes they need. With George as the face of the brand, Men's Wearhouse became a multi-billion dollar empire with hundreds of stores across the U.S. But then, in 2013, a bitter battle forced him to give it all up. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Pierre Thiam was robbed within days of arriving in New York City. It was 1989, and he had just traveled to the U.S. from Senegal to study chemistry and physics. This chance incident, however, set Pierre’s life on an entirely different course. Today, he’s a renowned chef, restaurant owner, cookbook author, and co-founder of Yolélé – a company working to introduce the world to an ancient West African grain called fonio. This week on How I Built This Lab, Pierre talks with Guy about his company’s work to circulate this nutrient-dense and drought-resistant food source. Pierre also shares how he overcame cultural norms to embrace his cooking career, and his take on the connection between colonization and the vulnerability of our global food systems. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

As a girl in 1970s London, Jo Malone learned how to make face creams by going to work with her mom at a private skin care clinic. By the time she was in her 20's, Jo was running her own skin care and cosmetics business, which eventually grew to include bath oils, scented candles, and fragrances under the brand Jo Malone London. Jo sold the brand to Estée Lauder in 1999 and then left the business after a life-changing diagnosis. She now has a fragrance company called Jo Loves, where she innovates with new kinds of scents and explores new ways to present them. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Growing up, Andrew Rea dreamed of becoming a Hollywood filmmaker. But the special effects production job he landed after college left him feeling…uninspired. After a series of creative defeats and mounting relationship troubles, his therapist suggested he find a new creative outlet. Andrew decided to make a short cooking video inspired by an episode of Parks and Recreation and uploaded it to YouTube... This week on How I Built This Lab, Guy asks Andrew about his journey from TV and movie buff to YouTube cooking sensation. His channel, Babish Culinary Universe now has nearly 10 million subscribers. Plus, Andrew candidly shares how his struggles with mental health have shaped his career. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In 2003, David Baszucki wanted to go viral. He had already sold a company that made educational software, and now he wanted to build something with mass appeal; with build-your-own avatars and myriad opportunities for users to compete and connect online. So in 2006, he and his co-founder Erik Cassel launched Roblox, a platform where you can play millions of different games, set in a wide array of virtual worlds. You can adopt a pet, escape from jail, build and run your own restaurant, or solve a murder mystery; you can even create games of your own. During the start of the pandemic in 2020, half of the kids in the US were keeping in touch via Roblox, and today, the company is worth over 28 billion dollars. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In 2014, friends Polina Veksler and Alex Waldman went clothes shopping at a major department store. To Polina’s surprise, Alex’s options were quite limited, and tucked away in one of the store’s less-traveled upper levels: the ‘plus-size’ section.  This unnerving realization that women could have such completely different shopping experiences at the same store drove Polina into research mode. She found that about 70% of women in the U.S. wear a size 14 or larger, but less than 20% of clothing is made in those sizes. Meanwhile, much of the double-digit-sized clothing available is fast fashion: not particularly well-fitting or built to last. Alex and Polina decided to create Universal Standard: a clothing brand where size was irrelevant – where any woman could shop and ask herself, “do I like this?” – not “does this come in my size?” This week on How I Built This Lab, Guy and Polina discuss the $100 billion opportunity to serve women of all sizes, as well as the challenges that come with building a size inclusive clothing brand. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

When Saeju Jeong moved from South Korea to the U.S. in his mid-20's, he barely knew anyone, didn't speak much English, and had only $5,000 in savings. Today, he's the CEO of Noom, one of the most popular weight loss/wellness apps in the U.S. Inspired by his late father—a doctor who criticized the profession for treating people only after they got sick—Saeju and his co-founder built their first fitness product in 2007. Several pivots later, they arrived at Noom, an app that carefully tracks what you eat, how you sleep and when you're stressed out. Noom has hinted it may go public this year—if so, the valuation could be as high as $10 billion. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Growing up in Colombia, Carlos Araque and his father liked to take apart bicycles and motorcycles then put them back together. This love of tinkering led Carlos to study engineering at MIT and eventually launch a career in the oil and gas industry. After 15 years of this work, Carlos realized he was uniquely suited to be a part of the global energy transition away from fossil fuels. He returned to his alma mater to help run a startup accelerator, and soon, Quaise Energy was born. This week on How I Built This Lab, Carlos shares how his company plans to drill the deepest holes ever to unlock the nearly limitless potential of geothermal energy. Carlos explains why he sees such promise with this energy source and how he spread his optimism to investors to raise more than $70 million and counting.  See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Sam and Mariah Calagione started dating in high school, and have been on a wild ride ever since. Their biggest, craziest adventure? Founding Dogfish Head Brewery and forever changing the landscape of American craft beer. From the moment Sam started home-brewing in his NYC apartment, he infused his beer with unusual ingredients like cherries, maple syrup, roasted chicory, and licorice. When he and Mariah officially launched Dogfish Head in 1995, it was the smallest brewery in America’s smallest state. 24 years (and countless pints) later, it was acquired by the Boston Beer Company for $300 million. Along the way, Sam and Mariah had one random experience after another: writing a bill to legalize their own brew-pub, winning best recipe at the Delaware Punkin Chunkin, and inviting Ricki Lake to their first tasting at Sam's apartment (spoiler alert: she showed up). See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

It wasn’t unusual for David Kelley to take calls from Steve Jobs in the middle of the night. This came with the territory, as David worked on designing dozens of products for Apple over the years – including their first computer mouse back in 1980.  Since then, David and his firm, IDEO, have helped all sorts of companies design new products. David also led the founding of Stanford’s d.school, where students learn to use design principles to solve complex problems. This week on How I Built This Lab, David shares stories from some of the most notable projects of his career. He discusses how diverse perspectives and backgrounds help teams generate new ideas, and explains how organizations can use design thinking to transform culture and foster innovation. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.