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GuidePost, A Podcast Series from The CRISPR Journal

20 Episodes

64 minutes | Jan 5, 2022
GuidePost Ep. 20: Eben Kirksey, Human Futures and Gene Editing
Anthropologist and author Eben Kirksey discusses his interest in somatic and hereditary human genome editing, particularly the impact on patients and practitioners, the history of CCR5 gene editing, and recalls his exceptional reporting in China in the wake of the CRISPR babies scandal, all of which is included in his riveting book “The Mutant Project” (2020).
51 minutes | Apr 26, 2021
GuidePost Ep. 19: David Liu, Precision Chemistry on DNA
The architect of base editing and prime editing, Harvard University chemist David R. Liu, recalls the genesis of the technology and discusses exciting preclinical results and potential future applications. {Sponsored by Pegasus Books}
62 minutes | Apr 6, 2021
GuidePost Ep. 18: Kevin Davies, CRISPR Chronicler
In this podcast, Mendelspod host Theral Timpson interviews Kevin Davies about his latest book, "Editing Humanity: The CRISPR Revolution and the New Era of Genome Editing". {Episode Sponsored by Mendelspod}
38 minutes | Oct 27, 2020
GuidePost Ep. 17: Dame Kay Davies, Guidance for Heritable Genome Editing
A conversation with Dame Kay Davies, University of Oxford geneticist and co-chair of the just-published international commission report on Hereditary Human Genome Editing (HHGE), which lays out a roadmap for if, when, and how we should proceed with embryo editing for couples with severe genetic diseases.
38 minutes | Dec 24, 2019
GuidePost Ep. 16: Luciano Marraffini, big time microbiologist
A discussion with Luciano Marraffini, the Rockefeller University microbiologist who has made several fundamental contributions in the brief history of CRISPR biology and genome editing.
17 minutes | Dec 11, 2019
GuidePost Ep. 15: Bartha Knoppers, bioethics and human rights
Canadian law professor Bartha Knoppers (McGill University) talks about her long-standing interests in genetics, bioethics, human rights and her latest role studying the clinical implementation of genome editing.
42 minutes | Nov 4, 2019
GuidePost Ep. 14: George Church, triple threat (reader/writer/editor)
A towering figure in genomics for three decades, George Church (Harvard Medical School) discusses pigs, mammoths, organoids, CRISPR babies, and why M stands for multiplexing.
40 minutes | Aug 21, 2019
Ep. 13: Edward Lanphier, chief editing officer
The recently retired founding CEO of Sangamo Therapeutics, Edward Lanphier, shares stories from two decades at the helm of the first biotech company to develop and take genome editing, using zinc finger nucleases, into the clinic.
43 minutes | Aug 6, 2019
Ep. 12: Dana Carroll, your moment of ZFN
One of the pioneers of gene editing, biochemist Dana Carroll (University of Utah), reflects on the crucial early years developing zinc finger nucleases and the prospects for genome editing.
32 minutes | Jul 9, 2019
Ep. 11: Adam Bolt, editor-turned-director
The director of “Human Nature” takes us behind the camera to discuss the making of the new documentary film that superbly captures the story of CRISPR.
65 minutes | Apr 10, 2019
Ep. 10: Alexis Komor & Nicole Gaudelli, base editing’s tenacious duo
While postdocs in David Liu’s lab at Harvard University, Alexis Komor (UCSD) and Nicole Gaudelli (Beam Therapeutics) developed a pair of CRISPR-based molecular machines known as base editors, capable of engineering precise single-base substitutions with enormous basic research and therapeutic implications.
50 minutes | Feb 5, 2019
Ep. 9: Emmanuelle Charpentier, CRISPR-Cas pioneer
In a French bistro in New York City, Emmanuelle Charpentier (Founding Director, Max Planck Unit for the Science of Pathogens, Berlin) discusses with Kevin Davies her nomadic career, the high points in her CRISPR journey, and previews her future plans.
20 minutes | Feb 5, 2019
Ep. 8: Sylvain Moineau, the phage whisperer
Sylvain Moineau (Laval University, Quebec) surveys the impact of two decades’ research in phage microbiology on the CRISPR gene editing revolution.
32 minutes | Feb 1, 2019
Ep. 1: Franciso Mojica, salt-lake secrets
GuidePost: A conversation with CRISPR pioneer Francisco Mojica is the first episode in a new podcast series from Mary Ann Liebert, Inc., publishers of The CRISPR Journal. Episode 1 is brought to you by MilliporeSigma CRISPR - Innovative reagents you can trust. In this episode Kevin Davis, Executive Editor of The CRISPR Journal, interviews Francisco Mojica from the University of Alicante.
30 minutes | Feb 1, 2019
Ep. 2: Virginijus Siksnys, DNA nucleases
In episode #2 of GuidePost, Kevin Davies (Executive Editor, The CRISPR Journal) travels to Lithuania to meet Virginijus Šikšnys, one of the central figures in the development of CRISPR gene editing, at his lab at the Institute of Biotechnology, Vilnius University. Siksnys is an expert in DNA-protein interactions, and in 2011-12, made critical contributions in transferring the Cas9 enzyme into E. coli and characterizing the mechanism by which it cuts DNA.
35 minutes | Feb 1, 2019
Ep. 4: Jacob Sherkow, CRISPR patents explained
In episode #4 of GuidePost, Jacob Sherkow (New York Law School) – one of the leading academic authorities on biotech patent law – explains the twists and turns of the ongoing CRISPR patent dispute.
22 minutes | Feb 1, 2019
Ep. 5: Neal Gutterson, editing plants
In episode 5 of GuidePost Podcast Series Neal Gutterson, Chief Technology Officer of Dow-Dupont’s agricultural division Corteva, discusses the exciting potential of gene editing/CRISPR to spur new crop strains and circumvent the contentious debate around GMOs.
19 minutes | Feb 1, 2019
Ep. 6: Kevin Holden, genome engineer
In episode #6 of GuidePost, Kevin Holden, Head of Synthetic Biology at Synthego Corporation, discusses the company’s Silicon Valley culture, growth, and its approach to providing new gene editing products for the CRISPR community.
24 minutes | Feb 1, 2019
Ep. 7: Kevin Esvelt, gene drives
Kevin Esvelt (MIT Media Lab) discusses his interest in gene drives and other gene editing approaches to combat tick-borne diseases and malaria.
37 minutes | Feb 3, 2018
Ep. 3: Rodolphe Barrangou, the CRISPR craze
The CRISPR Journal Executive Editor Kevin Davis interviews Editor-In-Chief Rodolphe Barrangou. This episode of GUIDEpost is brought to you by Synthego, who's vision is to turn biology into an information science with the ultimate goal of dramatically extending the healthy human lifespan by providing genome engineering solutions. Learn more at www.synthego.com.
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