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COVID-19 Evidence presented by InpharmD™

27 Episodes

6 minutes | 6 days ago
Association of Psychiatric Disorders and COVID-19
A retrospective, observational, cohort study done to assess whether a diagnosis of a schizophrenia spectrum disorder, mood disorder, or anxiety disorder is associated with mortality in patients with COVID-19.
8 minutes | 17 days ago
Preliminary Data on Johnson and Johnson Vaccine
A randomized, multicenter, double-blind, placebo-controlled, phase 1/2a clinical trial to evaluate the safety, reactogenicity, and immunogenicity of Ad26.COV2.S - a recombinant, replication-incompetent adenovirus serotype 26 (Ad26) vector encoding a full-length and stabilized SARS-CoV-2 spike (S) protein
8 minutes | 24 days ago
Clinical Characteristics of COVID-19 in Hematopoietic Stem-Cell Transplantation Recipients
An observational cohort study performed to describe characteristics and outcomes of hematopoietic stem-cell transplantation (HSCT) recipients after developing COVID-19
6 minutes | a month ago
Continuation versus discontinuation of RAAS inhibitors in hospitalized patients with COVID-19
A prospective, randomized, open-label trial performed to evaluate whether continuation of angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) is beneficial or harmful in patients who are admitted to hospital with COVID-19.
5 minutes | a month ago
Comparative Differences Between COVID-19 and Seasonal Influenza
A cohort study done to comparatively examine differences in risk of clinical manifestations and death among people admitted to hospital with coronavirus disease 2019 (COVID-19) and seasonal influenza.
10 minutes | a month ago
Efficacy and Safety of the Moderna mRNA-1273 SARS-CoV-2 Vaccine to Prevent COVID-19
A phase 3 randomized, stratified, observer-blinded, placebo-controlled trial to to assess the safety and efficacy of the mRNA-1273 vaccine in preventing SARS-CoV-2 infection. 
7 minutes | 2 months ago
Baricitinib plus Remdesivir for Hospitalized Adults with COVID-19 (ACTT-2)
A randomized, multicenter, adaptive, double-blind, placebo-controlled trial to evaluate whether the combination of baricitinib plus remdesivir was superior to remdesivir alone.
6 minutes | 2 months ago
Evaluation of Cloth Masks and Modified Procedure Masks as Personal Protective Equipment for the Public During the COVID-19 Pandemic
A comparative study done to evaluate the fitted filtration efficiency (FFE) of various consumer-grade and improvised face masks, as well as several popular modifications of medical procedure masks that are intended to improve mask fit or comfort.
7 minutes | 2 months ago
Simultaneous COVID-19 in Homozygous Twins
A case report describing two monozygotic twins with different clinical courses, despite having the same environment and genomic factors. 
6 minutes | 2 months ago
Adjusted BMI and risk of death due to COVID-19
A retrospective, cohort study conducted to determine the adjusted effect of body mass index (BMI), associated comorbidities, time, neighborhood-level sociodemographic factors, and other factors on risk for death due to COVID-19
7 minutes | 3 months ago
Safety and efficacy of inhaled nebulised interferon beta-1a (SNG001) for treatment of SARS-CoV-2 infection: a randomized, double-blind, placebo-controlled, phase 2 trial
A randomzied, double-blind, placebo-controlled, multicenter, phase 2, pilot trial conducted to determine whether inhaled SNG001 (recombinant interferon beta-1a) has the potential to reduce the severity of lower respiratory tract illness and accelerate recovery in patients diagnosed with COVID-19. 
8 minutes | 3 months ago
Bamlanivimab - SARS-CoV-2 Neutralizing Antibody LY-CoV555 in Outpatients with Covid-19
The purpose of this study was to evaluate the efficacy and safety of LY-CoV555 (bamlanivimab) in patients with recently diagnosed mild or moderate COVID-19 in the outpatient setting
8 minutes | 3 months ago
Safety and Immunogenicity of Two RNA-Based Covid-19 Vaccine Candidates
What does the evidence says on the safety and immunogenicity of pfizer's potential vaccine - BNT162b2 - as compared to other candidates?
6 minutes | 3 months ago
Levels of Severity of Depressive Symptoms Among At-Risk Groups During COVID-19
A cohort study examining levels of severity of depressive symptoms over time among individuals with high risk in the UK during the COVID-19 pandemic
6 minutes | 4 months ago
Efficacy of Tocilizumab in Patients Hospitalized with COVID-19
A randomized, double-blind, placebo-controlled trial conducted to assess if early intervention with interleukin-6 receptor blockade might limit COVID-19 progression to hypoxemic respiratory failure or death, reduce the risk of clinical worsening, and decrease the duration of supplemental oxygen use. 
7 minutes | 4 months ago
Genomic evidence for reinfection with SARS-CoV-2: a case study
A 25-year old male patient was infected on two separate occasions, with the second infection being symptomatically more severe than the first. Genomic analysis showed the two viral agents were genetically distinct.
7 minutes | 4 months ago
Remdesivir for the Treatment of Covid-19 — Final Report
The objective of this study was to evaluate the clinical efficacy and safety of remdesivir among hospitalized adults with laboratory-confirmed COVID-19.
7 minutes | 4 months ago
Effect of serum total testosterone and its relationship with other laboratory parameters on the prognosis of COVID-19 in SARS-CoV-2 infected male patients: a cohort study
The objective of the cohort study was to investigate the effect of serum testosterone and its relationship with other laboratory parameters on the prognosis of coronavirus disease 2019 in SARS-CoV-2 infected male patients
7 minutes | 5 months ago
Extracorporeal membrane oxygenation support in COVID-19: an international cohort study of the Extracorporeal Life Support Organization registry
The objective of this study was to use the Extracorporeal Life Support Organization (ELSO) Registry to report the epidemiology, treatment, outcomes, and hospital characteristics of patients receiving extracorporeal membrane oxygenation (ECMO)with a confirmed diagnosis of Corona Virus Disease 2019 (COVID-19).
8 minutes | 5 months ago
Risk Factors for Hospitalization, Mechanical Ventilation, or Death Among US Veterans With SARS-CoV-2 Infection
A study to determine the risk of hospitalization, mechanical ventilation, and death associated with infection; and to identify characteristics independently associated with these outcomes in patients who tested positive for severe acute respiratory syndrome coronavirus 2. Read more: inpharmd.com/covid 
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