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Comedian and actress Sarah Silverman feels ambivalent about being Conan O’Brien’s friend.   Sarah sits down with Conan once more to share her most irrational fear (and most embarrassing childhood memory), stories of family know-it-alls, and the thrills that come along with age-related hearing loss.

Conan talks to Anna in Bangkok about how to get her mom to stop yelling across the house, the most popular names in Thailand, and what it would be like to bring Conan to a ping pong show.

Comedian Vir Das feels unique about being Conan O’Brien’s friend.   Vir sits down with Conan to discuss faking appendicitis as a child, the first laugh he ever got on stage, the controversy over his “Two Indias” monologue, and his new special Vir Das: Landing. Later, Sona and David Hopping recount their adventures visiting every single Friends filming location.

Conan chats with Simon from Slovenia about his favorite specialty coffee shop and its unusual location.

Timothy Olyphant feels splendiferous about being Conan O’Brien’s friend.   Timothy and Conan sit down once more to discuss their unique friendship, being shot at in New Orleans while filming Justified: City Primeval, and a possible new talk show featuring the two of them.

Conan talks to Allan in Missouri about working as a crime scene investigator, surprising scenes she’s investigated, and which of Conan’s team would make the most skilled investigator.

Actor, writer, and comedian Ramy Youssef feels the inevitability of God coming into our lives about being Conan O’Brien’s friend.   Ramy sits down with Conan to discuss sharing personal history with castmates on his Hulu comedy series Ramy, the universal concept of “refinancing” with God, and filming in the West Bank. Plus, a bacteria sharing Conan’s name inspires debate over Conan and his team’s relative celebrity status.

Conan chats with Carles about working as a video game designer and what drag persona Conan would create for himself.

Actor Bryan Cranston feels stimulated about being Conan O’Brien’s friend.   Bryan sits down with Conan once more to dive into the details of his wild first sexual encounter in Salzburg, transitioning from physical comedy in Malcolm in the Middle to the high-stakes drama of Breaking Bad, how kindness and hard work are the key to a satisfying career, and the upcoming season 2 of Your Honor. Plus, Conan regretfully comes to terms with how Joop! cologne has impacted his life.

Conan speaks with Jill from Vulcan, Alberta about growing wetland plants in a commercial greenhouse, fainting goats, and what Conan would name a wetland species of his own discovering.

Actor Penn Badgley feels the dull echo of imposter syndrome about being Conan O’Brien’s friend.Penn sits down with Conan to discuss his journey to Hollywood as a child actor, the value of educating yourself, and THAT scene from his Netflix series YOU. Conan shares his love of Gossip Girl and pitches an alternate version as a sketch. Stick around for the end, where Conan and the team try on Tracy Morgan's favorite cologne.

Conan talks to David from New Rochelle, NY about being a congregational rabbi and what a clergy team meeting with Conan and the chums would look like.

Actor and comedian Ed Helms feels humbled about being Conan O’Brien’s friend.   Ed sits down with Conan to chat about the real-life Andy Bernard, learning the banjo, and exploring history’s greatest screwups with his podcast SNAFU. Plus, Conan and his team read a review of the podcast written by an AI.

In this special episode of Conan O’Brien IS a Fan, Conan sits down with Ashley Flowers of the podcast Crime Junkie to discuss what got her into true crime, why LA is the place to be for the genre, and her novel All Good People Here.

Former First Lady Michelle Obama feels less cautious about being Conan O’Brien’s friend.   Michelle returns to sit down with Conan once more to discuss her new book The Light We Carry, developing tools to deal with anxiety, the importance of working with one’s hands, and preparing for the empty nest.

Conan chats with Jackie from Ontario about working at the Toronto Humane Society, studying baboons, and tricks to get your cat to love you.

Actor Randall Park feels neither here nor there about being Conan O’Brien’s friend.   Randall sits down with Conan to discuss coming out as an actor to his parents, honing his comedic talents in workplace training videos, and his new show Blockbuster. Plus, Conan helps his team come up with age-appropriate toy ideas for their kids.

Conan talks to Alexandra about being a janitor in Antarctica, traveling the world, and which Disney Princess Conan identifies with the most.    

Actress Lizzy Caplan feels confused about being Conan O’Brien’s friend.   Lizzy sits down with Conan to talk about being well-positioned geographically, her new show Fleishman Is in Trouble, and the abandonment issues that come along with a career in acting. Later, Conan takes engineer Eduardo to task about distractions in the workplace.

Conan chats with Visa from Finland about coffee, the sauna, and playing in a metal band.