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The DiRECT trial ran counter to received wisdom by advocating a very-low-calorie, total-meal-replacement diet as a means not just of weight loss but also of weight maintenance for people with type 2 diabetes.

Trial dietitian Alison Barnes (Newcastle University, UK) speaks of her initial skepticism, and describes how the diet worked as a pragmatic way for people with type 2 diabetes to achieve weight loss and maintain it long term.

Find more on Medicine Matters diabetes

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