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Episode Info: Dr. Tim Jackson is a doctor of Physical Therapy. He also studied nutritional biochemistry, digestive health and its systemic effects, as well as functional endocrinology. He helps people with all sorts of disorders over at HealYourbody.org. He also does online consults through his Heal Your Body Program. In this episode we talked about: What MTHFR means: (It's not your first thought. I know what you were thinking.) It stands for Methylenetetrahydrofolate reductase. (Say that three times fast.) It basically means that if you have it, you lack the ability to activate folic acid into methyl-folate. Then you don't have the useable form of folate and you have too much folic acid sitting around. That's when disorders start popping up. Miscarriages have been associated with MTHFR. Best place to get tested: 23andme.com. You will just get the raw data, no interpretations. Get interpretations at livewello.com or MTHFRSupport.com. Heterozygous means you have one copy Homozygous means you have two copies Polymorphism is a SNP (Single-nucleotide polymorphism) Genetics refers to actual mutations someone might have. Trisomy or Down's Syndrome are examples. Epigenetics are modifiable risk factors, which give us a predisposition to certain diseases or disorders. The key word is modifiable. They are not set in stone. "HG can be the straw that breaks the camel's back." Allostatic load means the sum total of internal and external stressors on the body. "It can take a disease from subclinical to clinical" (expressed). "Any stressor can effect the expression of genes." Exposome means everything you've been exposed to in your life. You can have too little or too much methylation. This effect neurotransmitter production (mood disorders), T-cells (infection and allergies), and Glutithione (which controls free radicals). Can Hyperemesis Gravidarum be an allergy to the hormones, the placenta or the baby? Short answer....YES. Neuro-immune is more accurate than "Auto-immune" to describe this. Liver Detox: Phase 1: oxydation Phase 2: conjugation-methylation Phase 3: Transport to the cell Milk Thistle supports Phase 1 detox. If phase 2 is not adequate, the byproducts of phase 1 sit around causing oxidative stress. B vitamins, NAC (N-acetyl cysteine-precursor to glutithione), Glutithione and Glycine support Phase 2 detox. Oxidative Stress causes all disorders, which go through 3 stages. Stage 1: energetic imbalance (you don't feel bad in this stage) Stage 2: Functional: Fibromyalgia or chronic fatigue syndrome. You feel the effects but there are no biomarkers to show what's going on. Stage 3: lesional-can be seen on an MRI (like Multiple Sclerosis) Inflammation causes fatigue ad premature aging. Lipid Peroxidation: damage to cell membranes What to do about it: Support the methylation cycle Reduce oxidative stress Diet: Clean out processed foods and additives. Remove sugar and gluten. Consider removing dairy Heal your gut (mood disorders are related to leaky gut.) Just because y...
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