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Episode Info

Episode Info:

Here is a summary of this episode: In patients with liver impairment, it is better to use drugs that are metabolized by phase II enzymes or drugs that are not metabolized by the liver at all. Patients with severe renal impairment may also have liver impairment. Use ⅔ of the recommended dose. Benzodiazepines and Z-drugs are contraindicated in CO2 retainers and those with severe sleep apnea. Opiates are better than benzodiazepines in patients with terminal breathlessness. Download a PDF of this interview here Become a premium member of the Psychopharmacology Institute 

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