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BrainWaves is an academic neurology podcast whose mission is to educate medical providers through clinical cases and topical reviews in medicine and the humanities.
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#118 Subcortical kinds of cortical signs
3 days ago
Lesion localization is a critical skill for any neurologist. The so-called "cortical signs" are symptoms or exam findings which are often associated with cortical neuron injury--aphasia, neglect, gaze preference. But they are also seen after injury to subcortical structures, including white matter tracts, the thalamus, and basal ganglia. In this week's installment of the BrainWaves podcast, we'll attempt to localize subcortical lesions based on these major cortical signs. Produced by James E. Siegler. Music by Aussenseiter, Gnagno, Yshwa, and Kevin McLeod. BrainWaves' podcasts and online content are intended for medical education only and should not be used for clinical decision making. REFERENCES Maeshima S and Osawa A. Thalamic Lesions and Aphasia or Neglect. Current neurology and neuroscience reports. 2018;18:39. Bogousslavsky J, Regli F and Uske A. Thalamic infarcts: clinical syndromes, etiology, and prognosis. Neurology. 1988;38:837-48. Karnath HO, Himmelbach M and Rorden C. The subcortical anatomy of human spatial neglect: putamen, caudate nucleus and pulvinar. Brain. 2002;125:350-60. Lam YW and Sherman SM. Functional organization of the thalamic input to the thalamic reticular nucleus. J Neurosci. 2011;31:6791-9. Tijssen CC. Contralateral conjugate eye deviation in acute supratentorial lesions. Stroke; a journal of cerebral circulation. 1994;25:1516-9. Fridriksson J, den Ouden DB, Hillis AE, Hickok G, Rorden C, Basilakos A, Yourganov G and Bonilha L. Anatomy of aphasia revisited. Brain. 2018. Epub ahead of print. Nadeau SE and Crosson B. Subcortical aphasia. Brain Lang. 1997;58:355-402; discussion 418-23.Read more »