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Episode Info: In this nineteenth episode, Stephen Matlin introduces telomere biology. He details how testing services typically use Q-PCR which provides an average telomere length and why that doesn’t really mean anything. Read the transcript Instead the percentage of critically-short, measured using Q-FISH, does. Finally he chats about supplements – telomerase inducers – for growth. Topics we discussed in this episode Introduction to telomere biology Hayflick limit, senescent cells, apoptosis Telomeres and the hallmarks of aging Quantitative PCR derived average telomere length vs shortest telomeres Coefficient of variation of lab samples Role of supplements in supporting our telomeres and overall biological function Declining nutrition in even vegetables Telomerase inducers TA-65 and TAM-818 Telomerase enzyme Henrietta Lacks cells, cancer and the Hayflick limit Telomerase supplements and cancer Telomerase inducer Telomere Benefits Providing biological age scores using telomere measurements Telomere length and correlation with healthspan Improving upon biomarker Prostate Specific Antigen with Prostate Telomere Associate Variance Show links (Company Website) T.A. Sciences TA-65 (UK/Europe) T.A. Sciences TA-65 ( Hayflick, His Limit, and Cellular Ageing (Paper) The Hayflick Limit (Embryo Project Encyclopedia) The End-Replication Problem (Paper) Leucocyte Telomere Length And Risk Of Cardiovascular Disease: Systematic Review And Meta-analysis (Paper) Association Between Leucocyte Telomere Length And Cardiovascular Disease In A Large General Population In The United States (Paper) The Hallmarks of Aging (Paper) Coefficient of Variation (Wikipedia Entry) A Natural Product Telomerase Activator Lengthens Telomeres in Humans: A Randomized, Double Blind, and Placebo Controlled Study (Paper) The Telomerase Activator Ta-65 Elongates Short Telomeres And Increases Health Span Of Adult/old Mice Without Increasing Cancer Incidence (Paper) Discovery Of Potent Telomerase Activators: Unfolding New Therapeutic And Anti-aging Perspectives (Paper) The Nobel Prize in Physiology or Medicine 2009 (Website) Defy Time (Website) Telomere Benefits (Product Link) Mathematical Connection Between Short Telomere Induced Senescence Calculation And Mortality Rate Data (Paper) Comparison Of Telomere Length Measurement Methods (Paper) Beyond Average: Potential For Measurement Of Short Telomeres (Paper) The post You Should Measure the Length of Your Critically-Short Telomeres – EP19: Stephen Matlin (Life Length) appeared first on Quantified Health, Wellness & Aging Podcast. ...
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