If you go through life with "No Regrets", Aida won't have anything to take away from you in the Framework. But with our SHIELD team, those regrets have created an ugly world where HYDRA is in charge. Jeffrey Mace battles this virtual enemy with honor and persistence. Back at HYDRA headquarters, Daisy continues to suffer at the hands of Doctor Fitz, and awaits rescue by her friends. Coulson and Mace go to rescue an agent that turns out to be our old friend Tripp. But when an augmented May attacks them, a whole building comes down, and Mace has to make the ultimate sacrifice to save the innocent. A tragedy for sure, but it wakes up May and starts to turn the tables in our favor. Mount up, Flugleman, because Jay and Josh grab some Augmented Strength Serum on this week's episode of Agents of S.H.I.E.L.D.- Case Files.