The Ironman Executive
About This Show
Daniel Stickler, MD is the Ironman Executive. He selects topics that are all about advances designed to enhance human performance and upgrade our function. He explores the science and medical advances that will help all of us to become the ironman executive.
Most Recent Episode
Genetics and Genomics - How They Relate to Dietary Patterns
4 days ago
With today's guest Nicola Pirastu we learn the difference between several common genetic terms, how your diet choices may or may not be good for your personal health and how your diet can impact your genes and their expressions. Genetics Vs Genomics The terms genetics and genomics sound alike, and they are often used interchangeably. But there are some important distinctions and similarities between genetics and genomics and how they affect our dietary patterns. But firstly, what do they mean? Genetics is the study of heredity, or how the characteristics of living organisms are transmitted from one generation to the next via DNA, and it comprises genes, the basic unit of heredity. Genetics dates back to Darwin and scientist Lamarck, whose studies of pea plants in the mid-1800s established many of the rules of heredity. Genetics involves the study of specific and limited numbers of genes, or parts of genes, that have a known function. In biomedical research, scientists try to understand how genes guide the body’s development, cause disease or affect our eating or dietary patterns. Genomics, in contrast, is the study of the entirety of an organism’s genes – called the genome. Genomics is the branch of molecular biology concerned with the structure, function, evolution, and mapping of genomes. Genomics is a much newer field than genetics and became possible only in the last couple of decades due to technical advances in DNA sequencing and computational biology. (It is notable that the term genomics was first coined in 1986 by a Jackson Laboratory scientist, Tom Roderick, Ph.D.) Genomics play huge roles in our dietary patterns as they help us know why our body relates to different foods and why our food preferences may or may not affect our overall health. For example two men of the same age were placed on a diet and eat fruits and vegetables high in sodium and saturated fat. One develops hypertension, hypercholesterolemia, and eventually atherosclerosis, while the other lives a long life without such chronic disease. In another case, two postmenopausal women consume similar diets low in choline. One develops liver dysfunction due to the choline deficiency, but the other does not. Why individuals experience different health outcomes even though they eat similar diets and practice comparable lifestyles is an important question that
Rated 5 out of
Really awesome show
Have only listened to the first few shows but really enjoying what I am hearing; good info, quality guests, and good interactions.
Date published: 2014-08-14