Adaptive clinical trials offer a host of benefits when investigating both drugs and medical devices. By making use of a single technology platform that flexibly and seamlessly combines electronic data capture, randomization and supply management, sponsors are able to more efficiently and easily manage the critical aspects of adaptive trials. In this podcast, Corey Dunham, Senior Vice President for Biometrics at Aptiv Solutions, and Michael Remavich, Senior Director of Clinical Data Management at Aptiv Solutions discuss technological innovations that allow sponsors to design and execute adaptive trials. They discuss how new technologies allow for better management of multiple interim analyses and can facilitate data driven monitoring and real time data cleaning. They also touch on regulatory guidance and how these new approaches can minimize operational bias and maintain trial integrity.